Evaluation of the Qualitative Phytochemical Composition of Extracts of Picralima Nitida Seeds, Leaves and Bark
Keywords:
qualitative, phytochemical, composition ,extracts , Picralima nitida seeds, leaves and bark.Abstract
In West African traditional medicine, picralima nitida is frequently used to treat a variety of blood-related conditions, such as anemia and diabetes, as well as malaria, diarrhea, and inflammation. The ethno-medical use of several portions of this plant has been validated by strong scientific data; however, research on its contents has been restricted, and conflicting claims have been made regarding its safety profile. In this work, the qualitative phytochemical content of Picralima nitida seed, leaf, and bark extracts is determined.The results of the phytochemical study showed that the extractives had a high concentration of alkaloids, saponins, tannins, carbohydrates, and a moderate amount of flavonoids, ascorbic acid, and terpenoids. The bark showed 20% mortality at a dose of 5000 mg/kg, with an LD50 < 3,807.89 mg/kg, whereas the leaf and seed extracts had LD50 ≥ 5000 mg/kg (practically not dangerous).These abilities shown by the various extracts could be attributed to the phytoconstituents and some of the compounds identified in the GC-MS analysis.
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